Medicine Brand

Civodex Vet

Ciprofloxacin Hydrochloride 3 mg/mL + Dexamethasone 1 mg/mL

Strength

3 mg/mL

Dosage Form

Drops (eye/ear/nasal)

Indication

Civodex vet used against almost all types of bacterial diseases of eye e.g. Acute and chronic keratitis, conjunctivitis, pink eye, ophthalmitis caused by gram-possitive & gram-negative bacteria. It is also indicated in chronic anterior uveities, scleritis, episcleritis, myositis and corneal injury from chemical radiation or thermal burns or penetration of foreign bodies.

Mode of Action

Dexamethasone inhibits leukocyte infiltration at the site of inflammation. Ciprofloxacin inhibits DNA gyrase enzyme (specially type-II topoisomerase enzyme) which causes negative supercoiling of bacterial DNA, thus inhibit bacterial growth which causes death of bacteria.

Dose Guidance

Cattreatment
Topical

Dose

2 – 3

drops

Frequency

q4h to q6h

Duration

2 days

Purpose

treatment

2-3 drops into conjunctival sac(s) every four to six hours. During the initial 24 to 48 hours, the dosage may be increased to 2-3 drops every two hours

Cattletreatment
Topical

Dose

2 – 3

drops

Frequency

q4h - q6h

Duration

2 days

Purpose

treatment

2-3 drops into conjunctival sac(s) every four to six hours. During the initial 24 to 48 hours, the dosage may be increased to 2-3 drops every two hours

Contraindications

Ciprofloxacin should not be used together with the Chloramphenicol, Macrolides or Tetracycline.

Alternatives

— other brands with Ciprofloxacin Hydrochloride