Generic Formulation

Xylazine Hydrochloride

Indication

Sedation, chemical restraint and premedication; provides muscle relaxation and some analgesia.

Contraindications

Cattle are roughly ten times more sensitive than horses — use the species dose. Avoid in late pregnancy in cattle, where it stimulates the uterus. Cardiac disease; respiratory compromise.

Side Effects

Bradycardia, hypotension, respiratory depression, bloat in ruminants, vomiting in dogs and cats. Effects are reversible with an alpha-2 antagonist.

Pregnancy & Lactation

Avoid in the last trimester in cattle — may induce premature parturition.

Dose Guidance

DogIM/IV

Dose

0.5 – 1

mg/kg

Frequency

once

Duration

single dose days

Vomiting is common. Reversible with an alpha-2 antagonist. Verify against the product label before use.

CatIM/IV

Dose

0.5 – 1

mg/kg

Frequency

once

Duration

single dose days

Vomiting is common. Reversible with an alpha-2 antagonist. Verify against the product label before use.

CattleIM

Dose

0.05 – 0.1

mg/kg

Frequency

once

Duration

single dose days

Cattle are about ten times more sensitive than horses - use the cattle figure, not the equine one. Avoid in late pregnancy. Verify against the product label before use.

HorseIV

Dose

0.5 – 1.1

mg/kg

Frequency

once

Duration

single dose days

Verify against the product label before use.

BuffaloIM

Dose

0.05 – 0.1

mg/kg

Frequency

once

Duration

single dose days

Cattle are about ten times more sensitive than horses - use the cattle figure, not the equine one. Avoid in late pregnancy. Verify against the product label before use.

CowIM

Dose

0.05 – 0.1

mg/kg

Frequency

once

Duration

single dose days

Cattle are about ten times more sensitive than horses - use the cattle figure, not the equine one. Avoid in late pregnancy. Verify against the product label before use.

CalfIM

Dose

0.05 – 0.1

mg/kg

Frequency

once

Duration

single dose days

Cattle are about ten times more sensitive than horses - use the cattle figure, not the equine one. Avoid in late pregnancy. Verify against the product label before use.

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