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Medicine Brand

Duplocillin LA

Benzathine penicillin G 150,000 IU/mL + Procaine penicillin G 150,000 IU/mL

Strength

150,000 IU/mL

Dosage Form

Injection

Indication

Acts on bacteria cell wall => Inhibit transpeptidase => Hamper cross linkage (Peptidoglycan layer) of rapidly multiplying organisms => Call wall deficit is produced => Hyper-Osmotic environment is in the anterior of bacteria => Due to the action of autolysin/murein swelling and bursting occur => Death of bacteria (Bactericidal activity)

Dose Guidance

Generaltreatment
SC or IM

Dose

1

mL/10 kg bodyweight

Frequency

q72h

Duration

N/A

Purpose

treatment

as 30,000 IU/kg. Injection may be repeated at 72 hour intervals depending on clinical judgment given at a different injection site.

Alternatives

— other brands with Procaine penicillin G