Benzathine penicillin G 150,000 IU/mL + Procaine penicillin G 150,000 IU/mL
150,000 IU/mL
Injection
Acts on bacteria cell wall => Inhibit transpeptidase => Hamper cross linkage (Peptidoglycan layer) of rapidly multiplying organisms => Call wall deficit is produced => Hyper-Osmotic environment is in the anterior of bacteria => Due to the action of autolysin/murein swelling and bursting occur => Death of bacteria (Bactericidal activity)
Dose
1
mL/10 kg bodyweight
Frequency
q72h
Duration
N/A
Purpose
treatment
as 30,000 IU/kg. Injection may be repeated at 72 hour intervals depending on clinical judgment given at a different injection site.
Penicillin or procaine hypersensitivity. Never give intravenously — procaine causes acute reactions.
Duplocillin LA is a veterinary injection containing Benzathine penicillin G and Procaine penicillin G (150,000 IU/mL) from MSD Animal Health.
For treatment, the recommended dose of Duplocillin LA in general is 1 mL/10 kg bodyweight, given SC or IM, q72h. as 30,000 IU/kg. Injection may be repeated at 72 hour intervals depending on clinical judgment given at a different injection site.
In cattle, the withdrawal period for Duplocillin LA is meat 10 days and milk 4 days. Longer after repeated or high doses. Guidance only - verify against the product label, which is the legal authority.
In goat, the withdrawal period for Duplocillin LA is meat 10 days and milk 4 days. Guidance only - verify against the product label, which is the legal authority.
In sheep, the withdrawal period for Duplocillin LA is meat 10 days and milk 4 days. Guidance only - verify against the product label, which is the legal authority.
In pig, the withdrawal period for Duplocillin LA is meat 10 days. Guidance only - verify against the product label, which is the legal authority.
In buffalo, the withdrawal period for Duplocillin LA is meat 10 days and milk 4 days. Longer after repeated or high doses. Guidance only - verify against the product label, which is the legal authority.
In cow, the withdrawal period for Duplocillin LA is meat 10 days and milk 4 days. Longer after repeated or high doses. Guidance only - verify against the product label, which is the legal authority.
In calf, the withdrawal period for Duplocillin LA is meat 10 days and milk 4 days. Longer after repeated or high doses. Guidance only - verify against the product label, which is the legal authority.
In swine, the withdrawal period for Duplocillin LA is meat 10 days. Guidance only - verify against the product label, which is the legal authority.
Dosing information is provided for reference by qualified veterinary professionals and does not replace clinical judgement. Prices are indicative and may vary by region and retailer.