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Medicine Brand

Coctreat EP Vet

Sulphaquinoxaline 60 mg/gm + Amprolium 100 mg/gm + Vitamin K3 2 mg/gm + Ethopabate 5 mg/gm + Vitamin C 20 mg/gm

Strength

100 mg/gm

Dosage Form

Powder

Indication

This is an anticoccidial drug for treatment and control of coccidiosis in poultry. This combination is developed to take the advantage of the synergistic benefits of the three chemicals against a mixed infection of Eimeria acervulina, Eimeria maxima, Eimeria necatrix, Eimeria tenella, Eimeria brunette at relatively safe levels of each drug by itself.

Mode of Action

 Amprolium is a competitive antagonist of Thiamine. It causes deficiency of Thiamine in protozoan body & stops protozoan metabolism.  Sulphaquinoxalin is a competitive antagonist of PABA which stops metabolism of protozoa and other gram-positive & gram-negetive bacteria. Amprolium & Sulphaquinoxalin acts synergistically.  Ethopabate increases the spectrum of activity into two fold and overcomes resistance which may be developed by the combination of Amprolium & Sulphaquinoxalin.  Vitamin K3 prevents hemorrhage.  Vitamin C acts as an anti-stress factor and synthesizes Collagen to repair intestinal ulcer.

Dose Guidance

Poultryprevention
PO

Dose

0.25

gm/L

Frequency

q24h

Duration

3-4 days

Purpose

prevention

1gm/4 litre of drinking water for 3-4 days.

Poultrytreatment
PO

Dose

0.5

gm/L

Frequency

q24h

Duration

5-7 days

Purpose

treatment

1gm/2 litre of drinking water for 5-7 days

Alternatives

— other brands with Amprolium