Sulfamethoxazole / Sulphamethoxazole 100 mg/mL + Trimethoprim 20 mg/mL
100 mg/mL
Suspension
Poultry: Mycoplasmosis, Colibacillosis, Salmonellosis (Pullorum, Fowl typhoid), Fowl cholera, Gastroenteritis, CRD, Actinomycosis, Actinobacillosis, Coccidiosis, Infectious polyarthritis, Toxoplasmosis etc.
PABA (Para amino benzoic acid) is essential for bacterial growth & multiplication (synthesized by bacteria & supplied from environment). By different enzymatic process PABA is converted into Dihydrofolic acid at first & then Tetrahydrofolic acid. Tetrahydrofolic acid acts as a co-factor for single carbon metabolism & Nucleic acid synthesis. But due to structural similarity of PABA with Sulfonamides Dihydropteridin (essential for dihydrofolic acid synthesis) mistakenly combined with Sulfonamides instead of PABA. As a result Dihydrofolic acid synthesis is prevented. On the other side Trimethoprim prevents the formation of Tetrahydrofolic acid from Dihydrofolic acid. As a result bacterial DNA synthesis is prevented & bacteria are destroyed.
Dose
0.33
mL/L
Frequency
q24h
Duration
3 days
Purpose
prevention
1 ml suspension / 3 Litre of drinking water for 3 days.
Dose
0.67
mL/L
Frequency
q24h
Duration
4-6 days
Purpose
treatment
1 ml suspension / 1.5 Litre of drinking water for 4-6 days (minimum 15 mg. per Kg body weight).
Dose
0.2
mL/kg
Frequency
q24h
Duration
5-7 days
Purpose
treatment
10 ml suspension / 50 kg b. wt. daily for 5 - 7 days
Should not be used for the animal hypersensitive to active ingredients. Adequate fluid intake should be ensured during therapy. And Shake the content before use. To be dispensed only by or on the prescription of a registered Veterinary doctor.