Triclabendazole 900 mg + Levamisole Hydrochloride 600 mg
900 mg
Bolus
DoubledexTM M Vet bolus is a broad spectrum anthelmintic, effective against trematode & nematode worms of cattle, buffalo, sheep/goat etc. DoubledexTM M Vet bolus is used for the treatment of acute, sub acute and chronic Fascioliasis (infestation of trematodes) caused by Fasciola gigantica & F. hepatica. DoubledexTM M Vet bolus is also used against major stomach, intestine and respiratory nematodes of ruminants, such as • Haemonchus spp. • Ostertagia spp. • Cooperia spp. • Trichostrongylus spp. • Bunostomum spp. • Esophagostomum spp. • Trichuris spp. • Dictyocaulus spp.
DoubledexTM M Vet bolus contains two ideal anthelmintics like Triclabendazole & Levamisole. Triclabendazole acts against mature and immature flukes specially against liver flukes (Fascioliosis). It binds to the beta tubulin of the parasites and blocks polymerization of tubulin into microtubules. The process damages the integrity and transport functions of cells within the parasite and ultimately the parasite dies. Levamisole is an ideal broad spectrum anthelmintic that acts against respiratory and intestinal round worms. It causes lysis of worms by neuromuscular paralysis. Moreover, it acts as an immunomodulator.
Dose
19.5
mg/kg
Frequency
q24h
Duration
single dose days
Purpose
treatment
21–40 kg: 1/2 bolus. 41–75 kg: 1 bolus. 76–150 kg: 2 boli 151–225 kg: 3 boli. 226–300 kg: 4 boli. 301–375 kg: 5 boli. DoubledexTM M Vet bolus can be administered orally through water or by mixing with any feed (e.g., with molasses or by wrapping in a banana leaf) and feeding to the animal. Or, as directed by a registered veterinarian/consultant.
DoubledexTM M Vet bolus is contraindicated in animals hypersensitive to active ingredients.