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Medicine Brand

Doubledex Vet Bolus

Triclabendazole 1800 mg + Levamisole Hydrochloride 800 mg

Strength

1800 mg

Dosage Form

Bolus

Indication

DoubledexTM Vet bolus is a broad spectrum anthelmintic, effective against trematode & nematode worms of cattle, buffalo, sheep/goat etc. DoubledexTM Vet bolus is used for the treatment of acute, sub acute and chronic Fascioliasis (infestation of trematodes) caused by Fasciola gigantica & F. hepatica. DoubledexTM Vet bolus is also used against major stomach, intestine and respiratory nematodes of ruminants, such as • Haemonchus spp. • Ostertagia spp. • Cooperia spp. • Trichostrongylus spp. • Bunostomum spp. • Esophagostomum spp. • Trichuris spp. • Dictyocaulus spp

Mode of Action

DoubledexTM Vet bolus contains two ideal anthelmintics like Triclabendazole & Levamisole. Triclabendazole acts against mature and immature flukes specially against liver flukes (Fascioliosis). It binds to the beta tubulin of the parasites and blocks polymerization of tubulin into microtubules. The process damages the integrity and transport functions of cells within the parasite and ultimately the parasite dies. Levamisole is an ideal broad spectrum anthelmintic that acts against respiratory and intestinal round worms. It causes lysis of worms by neuromuscular paralysis. Moreover, it acts as an immunomodulator.

Dose Guidance

Cattletreatment
Oral

Dose

0.01

bolus/kg

Frequency

q24h

Duration

1 day

Purpose

treatment

Contraindications

DoubledexTM Vet bolus is contraindicated in animals hypersensitive to active ingredients

Alternatives

— other brands with Triclabendazole