Ivermectin 10 mg/mL
10 mg/mL
Solution
Used for the treatment and control ofEndo-parasite- Round worm Ecto-parasite- Tick, Lice, Mite & Flea
Ivermectin is a member of the macrocyclic lactone class of endectocides which have a unique mode of action. Compounds of the class bind selectively and with high affinity to glutamategated chloride ion channels which occur in invertebrate nerve and muscle cells. This leads to an increase in the permeability of the cell membrane to chloride ions with hyperpolarization of the nerve or muscle cell, resulting in paralysis and death of the parasite. Compounds of this class may also interact with other ligand-gated chloride channels, such as those gated by the neurotransmitter gamma-aminobutyric acid (GABA). The margin of safety for compounds of this class is attributable to the fact that mammals do not have glutamategated chloride channels, the macrocyclic lactones have a low affinity for other mammalian ligand-gated chloride channels and they do not readily cross the blood-brain barrier.
Dose
0.02
mL/kg
Frequency
q24h
Duration
N/A
Purpose
treatment
1 ml/50 kg body weight (0.2 mg per kg body weight)
Dose
0.02
mL/kg
Frequency
q24h
Duration
N/A
Purpose
treatment
1 ml/50 kg body weight (0.2 mg per kg body weight)
Dose
0.4
mL/kg
Frequency
q24h
Duration
10-14 days
Purpose
treatment
For internal parasite- 1 ml/25 kg body weight (Ivermectin 0.4 mg/kg body weight) once for single day. If necessary, can be repeated in 10-14 days. For external parasite: 1 ml/25 kg body weight (Ivermectin 0.4 mg/kg body weight) once for two consecutive days. If necessary, can be repeated in 10-14 days. In water body- 1 ml/decimal (per feet depth)